Quality Policy
Career Opportunities
Contact Us
Directions to ISS
Comments & Suggestions
Gregorio Weber Award
Internal Use
06/06/2007: ISS Awarded NIH Grant
03/03/2007: ISS Announces 2007 Gregorio Weber Award Winner
02/18/2006: ISS Announces 2006 Gregorio Weber Award Winner
09/01/2005: ISS Achieves ISO 9001:2000 Certification
01/05/2005: ISS Announces a New Version of OxiplexTS™
News Archive
Fluorescence Products
Alba FCS: Fluorescence Correlation SpectrometerAlba FLIM: Fluorescence Lifetime Imaging
PC1: Photon Counting Spectrofluorimeter
K2: Multifrequency Cross-Correlation Phase and Modulation Fluorometer
Chronos: Frequency-Domain Lifetime Spectrometer
ChronosBH: Time-Domain Lifetime Spectrometer
Modular Components for Building Spectrofluorometers
Phoenix: SLM Upgrade Packages
Software
Request Literature for Fluorescence Products
Biomedical Products
OxiplexTSImagent
Request Literature for Biomedical Products
Fluorescence Lifetime Standards
Lifetime Data of Selected Fluorophores
Excitation and Emission Wavelengths of Fluorophores
Fluorescent Probes Data Table
Fluorescence Standards for LEDs and Laser Diodes
Application & Technical Notes
Measurement Examples
Selected Publications
Laboratories & Societies
Selected References for the Use of PC1™ in Various Research Areas
-
Nanomaterials & Nanotechnology
Size Controlled Nano Meter Phase Structure in Thin Films of Blend Polythiophene Derivatives
Cui, H.-N., Teixeira, V., Zhang, J., Lee, H.
Thin Solid Films, 2006, 515(1), 301-306.Polymer/Gold Nanoparticle Nanocomposite Light-Emitting Diodes: Enhancement of Electroluminescence Stability and Quantum Efficiency of Blue-Light-Emitting Polymers
Park, J.H., Lim, Y.T., Park, O.O., Kim, J.K., Yu, J.-W., Kim, Y.C.
Chem. Mater., 2004, 16(4), 688-692.Probing Single-Stranded DNA Conformational Flexibility Using Fluorescence Spectroscopy
Murphy, M.C., Rasnik, I., Cheng, W., Lohman, T.M., Ha, T.
Biophys. J., 2004, 86, 2530–2537.Effects of Surface Passivation on Silicon Nanoparticle Photoluminescence
Harwell, D.E., Croney, J.C., Qin, W., Thornton, J.T., Day, J.H., Hajime, E.K., Jameson, D.M.
Chemistry Letters, 2003, 32(12), 1194-1195. -
Sensors
Individual Metal Ligands Play Distinct Functional Roles in the Zinc Sensor Staphylococcus aureus CzrA
Pennella, M.A., Arunkumar, A.I., Giedroc, D.P.
Journal of Molecular Biology, 2006, 356(5), 1124-1136.Structural Insights into Homo- and Heterotropic Allosteric Coupling in the Zinc Sensor S. aureus CzrA from Covalently Fused Dimers
Lee, S., Arunkumar, A.I., Chen, X., Giedroc, D.P.
J. Am. Chem. Soc., 2006, 128(6), 1937-1947. -
Biochemistry & Molecular Biology (Membranes, Nucleic Acids, Proteins)
Specificity in DNA Recognition by a Peptide from Papillomavirus E2 Protein
Faber-Barata, J., Mohana-Borges, R., Lima, L.M. T.R.
FEBS Letters, 2006, 580(8), 1919-1924.The Asymmetry in the Mature Amino-Terminus of ClpP Facilitates a Local Symmetry Match in ClpAP and ClpXP Complexes
Bewley, M.C., Graziano, V., Griffin, K., Flanagan, J.M.
Journal of Structural Biology, 2006, 153(2), 113-128.Methane Monooxygenase Hydroxylase and B Component Interactions
Zhang, J., Wallar, B.J., Popescu, C.V., Renner, D.B., Thomas, D.D., Lipscomb, J.D.
Biochemistry, 2006, 45(9), 2913-2926.The SRC-3/AIB1 Coactivator Is Degraded in a Ubiquitin- and ATP-Independent Manner by the REGγ Proteasome
Li, X., Lonard, D.M., Jung, S.Y., Malovannaya, A., Feng, Q., Qin, J., Tsai, S.Y., Tsai, M.-J., O'Malley, B.W.
Cell, 2006, 124(2), 381-392.Target Structure-Based Discovery of Small Molecules that Block Human p53 and CREB Binding Protein Association
Sachchidanand, Resnick-Silverman, L., Yan, S., Mutjaba, S., Liu, W.-J., Zeng, L., Manfredi J.J., Zhou, M.M.
Chemistry & Biology, 2006, 13(1), 81-90.Supramolecular Fluorophores for Biological Studies: Phenylene Vinylene-Amino Acid Amphiphiles
Harrington, D.A., Behanna, H.A., Tew, G.N., Claussen, R.C., Stupp, S.I.
Chemistry & Biology, 2005, 12(10), 1085-1091.Förster Resonance Energy Transfer Measurements Are Consistent with a Helical Bundle Model for Lipid-Free Apolipoprotein
Brouillette, C.G., Dong, W.-J., Yang, Z.W., Ray, M.J., Protasevich, I.I., Cheung, H.C., Engler, J.A.
Biochemistry, 2005, 44(50), 16413-16425.Probing the Interior of Peptide Amphiphile Supramolecular Aggregates
Tovar, J.D., Claussen, R.C., Stupp, S.I.
J. Am. Chem. Soc., 2005, 127(20), 7337-7345.Measurements of Internal Distance Changes of the 30 S Ribosome Using FRET with Multiple Donor–Acceptor Pairs: Quantitative Spectroscopic Methods
Majumdar, Z.K., Hickerson, R., Noller, H.F., Clegg, R.M.
Journal of Molecular Biology, 2005, 351(5), 1123-1145.Acid- and Pressure-Induced (Un)folding of Yeast Glutathione reductase: Competition Between Protein Oligomerization and Aggregation
Morais, A.C.S., Chapeaurouge, A., Ferreira, S.T.
The International Journal of Biochemistry & Cell Biology, 2005, 37(9), 1890-1899.A Bioactive Titanium Foam Scaffold for Bone Repair
Spoerke, E.D., Murray, N.G., Li, H., Brinson, L.C., Dunand, D.C., Stupp S.I.
Acta Biomaterialia, 2005, 1(5), 523-53.Effect of Modification of the Length and Flexibility of the Acyl Carrier Protein-Thioesterase Interdomain Linker on Functionality of the Animal Fatty Acid Synthase
Joshi, A.K., Witkowski, A., Berman, H.A., Zhang, L., Smith, S.
Biochemistry, 2005, 44(10), 4100-4107.Site-Directed Fluorescence Labeling Reveals Differences on the R-Conformer of Glucosamine 6-Phosphate Deaminase of Escherichia coli Induced by Active or Allosteric Site Ligands at Steady State
Sosa-Peinado, A., Gonzalez-Andrade, M.
Biochemistry, 2005, 44(46), 15083-15092.Separating the Contribution of Translational and Rotational Diffusion to Protein Association
Kuttner, Y.Y., Kozer, N., Segal, E., Schreiber, G., Haran, G.
J. Am. Chem. Soc., 2005, 127(43), 15138-15144.Reversible Equilibrium Unfolding of Triosephosphate Isomerase from Trypanosoma cruzi in Guanidinium Hydrochloride Involves Stable Dimeric and Monomeric Intermediates
Chanez-Cardenas, M.E., Perez-Hernandez, G., Sanchez-Rebollar, B.G., Costas, M., Vazquez-Contreras, E.
Biochemistry, 2005, 44(32), 10883-10892.Acyl-Coenzyme A Binding Protein Expression Alters Liver Fatty Acyl-Coenzyme A Metabolism
Huang, H., Atshaves, B.P., Frolov, A., Kier, A.B., Schroeder, F.
Biochemistry, 2005, 44(30), 10282-10297.Structural and Functional Characterization of Mycobacterium tuberculosis CmtR, a PbII/CdII-Sensing SmtB/ArsR Metalloregulatory Repressor
Wang, Y., Hemmingsen, L., Giedroc, D.P.
Biochemistry, 2005, 44(25), 8976-8988.Oligomeric State and Mode of Self-Association of Thermotoga maritima Ribosomal Stalk Protein L12 in Solution
Moens, P.D.J., Wahl, M.C., Jameson, D.M.
Biochemistry, 2005, 44(9), 3298-3305.A Detergent-like Mechanism of Action of the Cytolytic Toxin Cyt1A from Bacillus thuringiensis var. israelensis
Manceva, S.D., Pusztai-Carey, M., Russo, P.S., Butko, P.
Biochemistry, 2005, 44(2), 589-597.Domain Study of Bacteriophage P22 Coat Protein and Characterization of the Capsid Lattice Transformation by Hydrogen/Deuterium Exchange
Kang, S., Prevelige, Jr., P.E.
Journal of Molecular Biology, 2005, 347(5), 935-948.Entamoeba histolytica: Inhibition of Cellular Functions by Overexpression of EhGEF1, a Novel Rho/Rac Guanine Nucleotide Exchange Factor
Aguilar-Rojas, A., De Jesús Almaraz-Barrera, M., Krzeminski, M., Robles-Flores, M., Hernández-Rivas, R., Guillén, N., Maroun, R.C., Vargas, M.
Experimental Parasitology, 2005, 109(3), 150-162.Effect of pH and Ionic Strength on the Cytolytic Toxin Cyt1A: a Fluorescence Spectroscopy Study
Manceva, S.D., Pusztai-Carey, M., Butko, P.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 2004, 1699(1-2), 123-130.Inhibition of Yeast Glutathione Reductase by Trehalose: Possible Implications in Yeast Survival and Recovery from Stress
Sebollela, A., Louzada, P.R., Sola-Penna, M., Sarone-Williams, V., Coelho-Sampaio, T., Ferreira, S.T.
The International Journal of Biochemistry & Cell Biology, 2004, 36(5), 900-908.Effects of Protein Kinase C Dependent Phosphorylation and a Familial Hypertrophic Cardiomyopathy-Related Mutation of Cardiac Troponin I on Structural Transition of Troponin C and Myofilament Activation
Kobayashi, T., Dong, W.-J., Burkart, E.M., Cheung, H.C., Solaro, R.J.
Biochemistry, 2004, 43(20), 5996-6004.Conserved Cysteine 126 in Triosephosphate Isomerase Is Required Not for Enzymatic Activity but for Proper Folding and Stability
Gonzalez-Mondragon, E., Zubillaga, R.A., Saavedra, E., Chanez-Cardenas, M.E., Perez-Montfort, R., Hernandez-Arana, A.
Biochemistry, 2004, 43(11), 3255-3263.Dynamic Instability in a DNA-Segregating Prokaryotic Actin Homolog
Garner, E.C., Campbell, C.S., Mullins, R.D.
Science, 2004, 306, 1021-1025.Liver Fatty Acid-Binding Protein Colocalizes with Peroxisome Proliferator Activated Receptor and Enhances Ligand Distribution to Nuclei of Living Cells
Huang, H., Starodub, O., McIntosh, A., Atshaves, B.P., Woldegiorgis, G., Kier, A.B., Schroeder, F.
Biochemistry, 2004, 43(9), 2484-2500.The Biotin Repressor: Modulation of Allostery by Corepressor Analogs
Brown, P.H., Cronan, J.E., Grøtli, M., Beckett, D.
Journal of Molecular Biology, 2004, 337(4), 857-869.Detection of Tryptophan to Tryptophan Energy Transfer in Proteins
Moens, P.D.J., Helms, M.K., Jameson, D.M.
The Protein Journal, 2004, 23(1), 79-83.Cdc42 Regulates the Par-6 PDZ Domain through an Allosteric CRIB-PDZ Transition
Peterson, F.C., Penkert, R.R., Volkman, B.F., Prehoda, K.E.
Molecular Cell, 2004, 13(5), 665-676.Time-resolved Fluorescence Anisotropy Studies Show Domain-specific Interactions of Calmodulin with IQ Target Sequences of Myosin V
Bayley P., Martin S., Browne P., Royer C.
Eur Biophys J., 2003, 32(2), 122-7.The 2’-O- and 3’-O-Cy3-EDA-ATP(ADP) Complexes with Myosin Subfragment-1 are Spectroscopically Distinct
Oiwa, K., Jameson, D.M., Croney, J.C., Davis, C.T., Eccleston, J.F., Ansonz, M.
Biophys. J., 2003, 84, 634–642.Persistent Conformational Heterogeneity of Triosephosphate Isomerase: Separation and Characterization of Conformational Isomers in Solution
Moreau, V.H., Rietveld, A.W. M., Ferreira, S.T.
Biochemistry, 2003, 42(50), 14831-14837.Sterol Carrier Protein-2 Selectively Alters Lipid Composition and Cholesterol Dynamics of Caveolae/Lipid Raft vs Nonraft Domains in L-Cell Fibroblast Plasma Membranes
Atshaves, B.P., Gallegos, A.M., McIntosh, A.L., Kier, A.B., Schroeder, F.
Biochemistry, 2003, 42(49), 14583-14598.Ablation of the Liver Fatty Acid Binding Protein Gene Decreases Fatty Acyl CoA Binding Capacity and Alters Fatty Acyl CoA Pool Distribution in Mouse Liver
Martin, G.G., Huang, H., Atshaves, B.P., Binas, B., Schroeder, F.
Biochemistry, 2003, 42(39), 11520-11532.The Mechanism of Ras GTPase Activation by Neurofibromin
Phillips, R.A., Hunter, J.L., Eccleston, J.F., Webb, M.R.
Biochemistry, 2003, 42(13), 3956-3965.Structural and Biochemical Characterization of a Fluorogenic Rhodamine-Labeled Malarial Protease Substrate
Blackman, M.J., Corrie, J.E., Croney, J.C., Kelly, G., Eccleston, J.F., Jameson, D.M.
Biochemistry, 2002, 41, 12244-12252.Modulation of Pig Kidney Na+/K+-ATPase Activity by Cholesterol: Role of Hydration
Sotomayor, C.P., Aguilar, L.F., Cuevas, F.J., Helms, M.K., Jameson, D.M.
Biochemistry, 2000, 39, 10928-10935. -
High Pressure Cell Measurements
Determination of the Activation Volume of PLCβ by Gβγ-Subunits through the Use of High Hydrostatic Pressure
Scarlata, S.
Biophys. J., 2005, 88, 2867–2874.Determination of the Volume Changes for Pressure-Induced Transitions of Apomyoglobin between the Native, Molten Globule, and Unfolded States
Vidugiris, G.J.A., Royer, C.A.
Biophys. J., 1998, 75, 463–470. -
Pharmaceutical Chemistry
A High-Throughput Resonance Energy Transfer Assay for Staphylococcus aureus DNA Ligase
Benson, E.L., Tomich, P.K., Wolfe, M.L., Choi, G.H., Hagadorn, J.C., Mutchler, V.T., Garlick, R.L.
Analytical Biochemistry, 2004, 324(2), 298-300.Kinase Inhibitors: Not Just for Kinases Anymore
McGovern, S.L., Shoichet, B.K.
J. Med. Chem., 2003, 46(8), 1478-1483. -
Physical Chemistry
On the Use of Theoretical Tools in the Study of Photophysical Properties of the New Eu(fod)3 Complex with Diphenbipy
Dos Santos, E.R., dos Santos, M.A., Freire, R.O., Júnior, S.A., Barreto, L.S., de Mesquita, M.E.
Chemical Physics Letters, 2006, 418(4-6), 337-341.Spectroscopic Properties of the Eu(fod)3Phen–NO Incorporated Carboxylate Glass
Beltrão, M.A., Santos, M.L., Mesquita, M.E., Barreto, L.S., da Costa, Jr., N.B., Freire, R.O., dos Santos, M.A.C.
Journal of Luminescence, 2006, 116(1-2), 132-138.White Light Emission From a Polymer Bilayer by Incomplete Cascade Energy Transfer
Park, J.H., Park, O.O., Kim, J.K., Yu, J.-W., Kim, Y.C.
Current Applied Physics, 2006, 6(4), 640-643.White Polymer Light-Emitting Devices From Ternary-Polymer Blend with Concentration Gradient
Park, J.H., Lee, T.-W., Kim, Y.C., Park, O.O., Kim, J.K.
Chemical Physics Letters, 2005, 403(4-6), 293-297.α-Crystallin Binding in Vitro to Lipids from Clear Human Lenses
Grami, V., Marrero, Y., Huang, L., Tang, D., Yappert, M.C., Borchman, D.
Experimental Eye Research, 2005, 81(2), 138-146.Remote and Adjacent Excited-State Electron Transfer At TiO2 Interfaces Sensitized to Visible Light with Ru(II) Compounds
Liu, F., Meyer, G. J.
Inorg. Chem., 2005, 44(25), 9305-93.Spectroscopic Studies of the Intermolecular Interactions of Congo Red and Tinopal CBS with Modified Cellulose Fibers
Yamaki, S.B., Barros, D.S., Garcia, C.M., Socoloski, P., Oliveira, Jr., O.N., Atvars, Langmuir, T.D.Z.
2005, 21(12), 5414-5420.Diffusion of a Single Component in a Binary Polymer Blend Upon Annealing Monitored by Fluorescence Microspectroscopy
De Andrade, M.L., Atvars, T.D.Z.
Macromolecules, 2004, 37(25), 9626-9630.Photophysical Study in Blends of Poly(alkyl methacrylate-Co-styrene)/Polystyrene
De Andrade, M.L., Atvars, T.D.Z.
Macromolecules, 2004, 37(24), 9096-9108.Optoelectronic and Photophysical Properties of Polyfluorene Blends as Side-Chain Length and Shape
Byun, H. Y., Chung, I. J., Shim, H.-K., Kim, C. Y.
Macromolecules, 2004, 37(18), 6945-6953.Hole-Transporting Property of a Chemically Hybridized Poly(vinylcarbazole)-Fullerene
Park, J.H., Park, O.O., Kim, J., Yu, J.-W., Kim, J.K., Kim, Y.C.
Current Applied Physics, 2004, 4(6), 659-662.Surface Treatment to Enhance the Quantum Efficiency of Semiconductor Nanocrystals
Jang, E., Jun, S., Chung, Y., Pu, L.
J. Phys. Chem. B., 2004, 108(15), 4597-4600.Dynamic and Static Fluorescence Spectroscopy Applied to Miscibility of Poly(n-butyl methacrylate-co-styrene) with Polystyrene and Morphological Analysis by Epifluorescence Microscopy
De Andrade, M.L., Atvars, T.D.Z.
J. Phys. Chem. B., 2004, 108(13), 3975-3984.Photo and Electroluminescence Studies of Poly(methyl methacrylate-co-9-anthryl methyl methacrylate)
De Deus, J.F., Andrade, M.L., Atvars, T.D.Z., Akcelrud, L.
Chemical Physics, 2004, 297(1-3), 177-186.The Effects of Alkyl Side-Chain Length and Shape of Polyfluorenes on the Photoluminescence Spectra and the Fluorescence Lifetimes of Polyfluorene Blends with Poly(n-vinylcarbazole)
Byun, H.Y., Chung, I.J., Shim, H.-K., Kim, C.Y.
Chemical Physics Letters, 2004, 393(1-3), 197-203.Photophysical Study of a Conjugated–non-Conjugated PPV-Type Electroluminescent Copolymer
Machado, A.M., Da Motta Neto, J.D., Cossiello, R.F., Atvars, T.D.Z., Ding, L., Karasz, F.E., Akcelrud, L.
Polymer, 2005, 46(8), 2452-2460.Enhanced Light Output in Bilayer Light-Emitting Diodes with Film Thickness Variations
Park, J.H., Lee, K.-J., Park, O.O., Yu, J.-W., Kim, Y.C., Kim, J.K.
Chemical Physics Letters, 2004, 386 (1-3),101-104.Orbital Control of the Color and Excited State Properties of Formylated and Fluorinated Derivatives of Azulene
Shevyakov, S.V., Li, H., Muthyala, R., Asato, A.E., Croney, J.C., Jameson, D.M., Liu, R.S.H.
J. Phys. Chem. A., 2003, 107(18), 3295-3299.Immobilized Particle Arrays: Coalescence of Planar- and Suspension-Array Technologies
Stevens, P.W., Wang, C. H. J., Kelso, D.M.
Anal. Chem., 2003, 75(5), 1141-1146.