Measurements Acquired Using OxiplexTS™

The plots below show measurements on human calf muscle during exercise. Changes in hemoglobin oxygenation and concentration can be correlated with various clinical conditions. For example, an increase in oxygenated hemoglobin concentration during exercise accompanied by no change or an increase in de-oxygenated hemoglobin concentration may indicate a venous occlusion which restricts the flow of de-oxygenated hemoglobin out of tissue. Similarly, arterial occlusions may be identified by significant decreases in oxygenated hemoglobin concentrations. The magnitude of hemoglobin changes as well as the rate of change may correlate with the type and extent of vascular disease. A wide variety of tissue oxygenation research is possible.

Figure (a) shows the ratio of Oxygenated to Total Hemoglobin Concentration as a percent. Also shown are some of the measurement parameters that can be correlated with physiological conditions including baseline (pre-exercise) value, change as a result of exercise, rates of change at the beginning and end of exercise, and final value after recovery from exercise.

Figure (b) shows Total Hemoglobin Concentration (in micromoles per liter).

Figure (c) shows Deoxygenated Hemoglobin Concentration.

Figure (d) shows Oxygenated Hemoglobin Concentration.