OxiplexTS™

Near-Infrared, Non-Invasive Tissue Oximeter

OxiplexTS™ is a revolutionary new device allowing the measurement of oxygenated and de-oxygenated hemoglobin concentrations in tissue. The device works by emitting Near Infrared (NIR) light into tissue at known distances from a collector. Light of two different wavelengths is used and the light is modulated at an RF frequency of 110 MHz. The collected light is measured and processed, and the absorption and scattering coefficients of the medium are determined. Once the absorption and scattering are determined, the assumption that hemoglobin is the only significant absorber is applied and the oxygenated and de-oxygenated hemoglobin concentrations are calculated.

The unique feature of the ISS OxiplexTS™ is that it uses the theory of photon migration through highly scattering media. This patented technology allows for the first time the absolute measurement of absorption and scattering in a highly scattering medium such as human tissue.

Since OxiplexTS™ measures the absorption and scattering of tissues directly, it does not require any calibration, estimation, or assumption about scattering in order to make an accurate measurement of absorption and, hence, hemoglobin concentrations. This unique ability to separate scattering from absorption sets the ISS OxiplexTS™ above all other NIR tissue oximeter technologies.

Notice: Investigational device. Limited by Federal (or United States) law to investigational use. The ISS OxiplexTS is presently used for research only.