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Gregorio Weber Award
03/03/2007: ISS Announces 2007 Gregorio Weber Award Winner
02/18/2006: ISS Announces 2006 Gregorio Weber Award Winner
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01/05/2005: ISS Announces a New Version of OxiplexTS™
12/23/2004: ISS Introduces Light Emitting Diodes (LEDs) for the Study of Proteins
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Fluorescence Products
Alba FCS: Fluorescence Correlation SpectrometerAlba FLIM: Fluorescence Lifetime Imaging
PC1: Photon Counting Spectrofluorimeter
K2: Multifrequency Cross-Correlation Phase and Modulation Fluorometer
Chronos: Frequency-Domain Lifetime Spectrometer
ChronosBH: Time-Domain Lifetime Spectrometer
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Phoenix: SLM Upgrade Packages
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OxiplexTSImagent
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K2™
Multifrequency Cross-Correlation Phase and Modulation Fluorometer

With over 100 installed units all over the world, the K2™ family of
Multifrequency Cross-Correlation Phase and Modulation Fluorometers
represents a solid and well-proven approach to fluorescence and phosphorescence
instrumentation for the research laboratory. K2™'s are used by researchers
at the ETH in Zurich, Switzerland, the MIT in Cambridge, MA, the NIH in
Rockville, MD, or at the NASA research facility in Huntsville, AL.
For a more comprehensive list of users, click here.
Its optical design and automatic instrument control are state-of-the-art for steady-state and time-resolved fluorescence measurements. Full automation and the user-friendly Vinci software package make the instrument easy to use for both, the student and the scientist.
For a demonstration of the acquisition and analysis capabilities of Vinci - Multidimensional Fluorescence Spectroscopy, choose between the following two options:
- Embedded Flash File
- Executable Presentation File (Use the Esc key to exit the file)
Measurements (Steady-State Fluorescence)
- Corrected excitation and emission spectra
- Excitation-emission matrices
- Excitation polarization spectra
- Polarization (anisotropy) measurements
- Millisecond kinetics in photon counting mode
- Dual-wavelength-ratiometric excitation or emission measurements
Measurements (Time-Resolved Fluorescence)
- Multiple decay times from millisecond to picosecond time scale
- Anisotropy decays
- Phase-resolved spectra (up to 3 components in a mixture)
- Time-resolved spectra
- Lifetime measurements with blank subtraction
Features
- Lifetime measurement capabilities from 1 millisecond to 1 picosecond
- Complete lifetime scans in less than one minute on routine samples with proprietary FastScan technology
- A compact footprint and a short optical pathlength for maximum sensitivity and efficient light coupling into the sample
- T-format and parallel beam optical design for fast and precise polarization measurements
- Full automation of all instrument components (cuvette holder, polarizers, shutters, filterwheel, monochromators, and stirrers)
- PC-controlled integration of termperature bath, titrator, stopped-flow apparatus and pressure pump
- Measurement of fast kinetics data with one millisecond resolution in photon counting mode
- 80 MHz pre-amplifier discriminators delivering linearity up to over eight million counts per second on each channel
- Flexible instrument configuration
- Upgradeable with Ti:Sapphire laser and laser diodes
Three models of K2™ are available, and each comes fully automated and upgradeable to the next level model:
K2™-001 K2™-FastScan
The FastScan is our most popular model: lifetime data acquisition on a routine sample can be acquired in less than one minute using either a lamp or a laser. The cross-correlation is user-selectable up to 5000 Hz and data acquisition is performed through a FFT routine; the instrument covers the modulation frequency range from 300 KHz up to 350 MHz with a lamp and up to 450 MHz using a cw laser.
K2™-002 1.2 GHz Upgrade
This model requires a mode-locked laser as excitation source and a microchannel plate detector (MCP-PMT) for the collection of fluorescence. Alternatively, a laser diode can be utilized as the light source to measure frequency responses up to about 1 GHz. The cross-correlation is user-selectable up to 5000 Hz and data acquisition is performed through a FFT routine. It includes the FastScan upgrade and operates at modulation frequency up to 1.2 GHz.
K2™-003 6 GHz Upgrade
The K2™-003 is an upgrade of the K2™-002: it operates in the frequency range up to 6 GHz.

